Hafid Ait-Oufella Selected Research

Rupture

11/2022	JAK2V617F mutation drives vascular resident macrophages toward a pathogenic phenotype and promotes dissecting aortic aneurysm.
9/2017	Gingival fibroblasts protect against experimental abdominal aortic aneurysm development and rupture through tissue inhibitor of metalloproteinase-1 production.
10/2013	Natural regulatory T cells limit angiotensin II-induced aneurysm formation and rupture in mice.
7/2013	Angiotensin II promotes thoracic aortic dissections and ruptures in Col3a1 haploinsufficient mice.
2/2010	TGF-beta activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II-infused mice.

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Hafid Ait-Oufella Research Topics

Disease

28	Atherosclerosis 11/2023 - 02/2006
14	Inflammation (Inflammations) 01/2023 - 08/2008
12	Critical Illness (Critically Ill) 01/2024 - 01/2014
10	COVID-19 01/2024 - 01/2021
9	Septic Shock (Toxic Shock Syndrome) 04/2024 - 09/2013
7	Pneumonia (Pneumonitis) 01/2023 - 01/2014
7	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 03/2013
6	Hemorrhage 01/2024 - 07/2020
5	Sepsis (Septicemia) 01/2024 - 01/2022
5	Rupture 11/2022 - 02/2010
4	Neoplasms (Cancer) 01/2022 - 01/2018
4	Myocardial Infarction 12/2021 - 02/2006
4	Abdominal Aortic Aneurysm 01/2021 - 10/2013
4	Infections 12/2017 - 10/2007
4	Aneurysm (Aneurysms) 09/2017 - 02/2010
3	Hemolysis 01/2023 - 08/2019
3	Thrombosis (Thrombus) 01/2023 - 01/2019
3	Rheumatoid Arthritis 10/2021 - 01/2019
3	Coronary Artery Disease (Coronary Atherosclerosis) 10/2021 - 03/2013
3	Psoriasis (Pustulosis Palmaris et Plantaris) 10/2021 - 01/2019
3	Atherosclerotic Plaque (Atheroma) 11/2020 - 08/2006
3	Stroke (Strokes) 11/2020 - 02/2006
3	Aortic Rupture 09/2017 - 07/2013
2	Shock 01/2024 - 12/2023
2	Thrombocytopenia (Thrombopenia) 12/2023 - 11/2023
2	Hypotension (Low Blood Pressure) 10/2023 - 07/2022
2	Aortic Dissection 11/2022 - 09/2017
2	Ventricular Remodeling 01/2021 - 05/2015
2	Fibrosis (Cirrhosis) 01/2021 - 07/2014
2	Wounds and Injuries (Trauma) 10/2020 - 07/2020
2	Anemia 10/2020 - 07/2020
2	Aortic Aneurysm (Aneurysm, Aortic) 01/2017 - 02/2010
2	Hypertension (High Blood Pressure) 01/2017 - 07/2013
1	Multiple Organ Failure (MODS) 04/2024
1	Renal Insufficiency (Renal Failure) 04/2024
1	Disseminated Intravascular Coagulation 04/2024
1	Cardiotoxicity 03/2024
1	Purpura 01/2024
1	Mycoses (Diseases, Fungus) 08/2023
1	Cough 01/2023
1	autosomal recessive Candidiasis familial chronic mucocutaneous 01/2023
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2023
1	Acute Kidney Injury (Acute Renal Failure) 01/2023
1	Eosinophilia 01/2023

Drug/Important Bio-Agent (IBA)

8	Apolipoproteins E (ApoE)IBA 01/2023 - 03/2012
7	CytokinesIBA 10/2021 - 06/2009
7	Angiotensin IIIBA 01/2021 - 02/2010
5	Lactic Acid (Lactate)FDA LinkGeneric 04/2024 - 01/2021
5	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2017
5	Monoclonal AntibodiesIBA 10/2021 - 08/2010
5	LDL Receptors (LDL Receptor)IBA 01/2019 - 08/2006
4	Norepinephrine (Noradrenaline)FDA LinkGeneric 04/2024 - 07/2022
4	Interleukin-6 (Interleukin 6)IBA 01/2024 - 01/2018
4	LipidsIBA 01/2023 - 02/2006
4	Oxygen (Dioxygen)IBA 01/2023 - 01/2022
4	Peptides (Polypeptides)IBA 01/2022 - 03/2012
4	Interleukin-10 (Interleukin 10)IBA 01/2019 - 10/2013
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2024 - 01/2023
3	CholesterolIBA 11/2023 - 01/2021
3	BilirubinIBA 01/2023 - 08/2019
3	Triggering Receptor Expressed on Myeloid Cells-1IBA 10/2022 - 09/2019
3	ApolipoproteinsIBA 01/2019 - 03/2012
3	ErbB Receptors (EGF Receptor)IBA 06/2018 - 01/2018
2	AlbuminsIBA 01/2024 - 01/2018
2	tocilizumab (atlizumab)FDA Link 01/2023 - 01/2022
2	Dexamethasone (Maxidex)FDA LinkGeneric 01/2023 - 01/2023
2	AntibodiesIBA 12/2022 - 02/2020
2	RNA (Ribonucleic Acid)IBA 11/2022 - 10/2022
2	Acetylcholine (Acetylcholine Chloride)FDA Link 06/2022 - 01/2018
2	Blocking AntibodiesIBA 10/2021 - 01/2019
2	Lipoproteins (Lipoprotein)IBA 01/2021 - 05/2014
2	IronIBA 10/2020 - 07/2020
2	Erythropoietin FDA Link 10/2020 - 07/2020
2	Anti-Bacterial Agents (Antibiotics)IBA 12/2017 - 01/2014
2	Secretory Phospholipases A2IBA 05/2014 - 03/2013
2	Transforming Growth Factor beta (TGF-beta)IBA 12/2013 - 02/2010
2	CollagenIBA 07/2013 - 03/2012
2	AntigensIBA 03/2012 - 02/2006
1	AnthracyclinesIBA 03/2024
1	Urea (Carbamide)FDA LinkGeneric 01/2024
1	Hemostatics (Antihemorrhagics)IBA 01/2024
1	Metformin (Glucophage)FDA LinkGeneric 01/2023
1	Immunosuppressive Agents (Immunosuppressants)IBA 01/2023
1	AnticoagulantsIBA 01/2023
1	Heparin (Liquaemin)FDA LinkGeneric 01/2023
1	Proteins (Proteins, Gene)FDA Link 01/2023
1	Methylprednisolone FDA LinkGeneric 01/2023

Therapy/Procedure

16	Therapeutics 10/2023 - 08/2010
6	Resuscitation 04/2024 - 09/2013
5	Artificial Respiration (Mechanical Ventilation) 01/2023 - 07/2014
4	Length of Stay 01/2022 - 04/2016
2	Platelet Transfusion (Blood Platelet Transfusions) 12/2023 - 11/2023
2	Renal Replacement Therapy (Therapies, Renal Replacement) 08/2023 - 07/2014
2	Noninvasive Ventilation 07/2022 - 07/2022
2	Lasers (Laser) 06/2022 - 09/2013
2	Critical Care (Surgical Intensive Care) 10/2020 - 07/2020
2	Erythrocyte Transfusion 10/2020 - 07/2020
2	Contraindications 10/2020 - 07/2020
2	Catheters 05/2015 - 09/2010
1	Cardiopulmonary Bypass (Heart-Lung Bypass) 01/2023